Research
Research
last update: 2023-06-20
Decode the mechanisms governing CNS (brain and retina) immune tolerance and privilege in the CNS and its barriers and associated lymphoid organs
Unravel the roles of microglia, border-associated macrophages, dendritic cells, T cells, and endothelial cells and their interactions in CNS autoimmunity (multiple sclerosis, uveitis), inflammation (Alzheimer's disease), and infections (meningitis, encephalitis, and retinitis)
Characterize the immunological niches in CNS barriers (meninges, choroidal plexus, RPE/choroid, ciliary body, BBB/BRB) and fluids (CSF, aqueous humor) and identify their roles in regulating immune homeostasis and inflammation in the CNS